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Why are generic pills cheaper than the brand name ones?

The principal reason for the reduced price of generic medicines is that the creation of the generic drug runs up less cost and therefore a lower price can be offered and still maintain profitability.
Manufacturers of generic drugs are mainly able to avoid the following three costs that brand name pharmaceutical companies incur: (1) costs associated with the research and development of the drug; (2) costs associated obtaining regulatory approval (i.e. proving safety and efficacy of a drug); and (3) marketing costs.
First, Generic manufacturers do not incur the cost of drug discovery and instead reverse-engineer existing brand name drugs to allow them to manufacture bioequivalent versions.
Second, generic manufacturers do not bear the burden of proving the safety and efficacy of the drugs through clinical trials - rather, generic manufacturers must prove the generic drug’s bioequivalancy to the existing drug.
Third, these companies receive the large benefit of the marketing and advertising that goes into pushing the innovator drug. The brand name drug has to prove itself in the eyes of the consumer, generic ones do not. The drugs that generic manufacturers are selling have been on the market for usually a decade or more and do not need additional advertising. For the same reason, generic manufacturers also do not give away sample doses to promote their products. The significant research, development and marketing costs incurred by the large pharmaceutical companies in introducing a new drug to the market is often cited as the reason for the high cost of new agents - they wish to recover these costs before the patent expires. Generic manufacturers do not incur these costs, with bioequivalence testing and manufacturing costing relatively little, and are able to charge significantly less than the brand.

Generic ReviaOther / Generic Revia
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Drug Name

Revia (Naltrexone)

Drug Uses

Revia is used for treating alcoholism and narcotic (opioid) addiction in adults, as part of a complete treatment program. It may also be used to treat other conditions as determined by your doctor.

How Taken

Use Revia as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Revia by mouth with or without food.

Revia should not be taken until the naltrexone challenge test is negative.

Before taking Revia , you must be willing to take Revia to help with alcohol dependence, you must be free of substance abuse for 7 to 10 days, you must not have any severe or active liver or kidney problems, and you must not have any other medical problems or conditions that make taking Revia inadvisable.

Drug Class and Mechanism

Revia is a narcotic antagonist. It is thought to work by blocking the effects of injectable opioids (e.g., heroin, narcotic pain relievers). It has also been shown to decrease alcohol consumption.

Missed Dose

If you miss a dose of Revia, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store Revia at 77 degrees F (25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Revia out of the reach of children and away from pets.

Warnings/Precautions

Do not use Revia if:

  • you are allergic to any ingredient in Revia;
  • you are taking narcotic medications for pain, are dependent on narcotics, are experiencing withdrawal symptoms from narcotics, have failed the challenge test with Revia , or have tested positive for narcotics;
  • you have hepatitis, liver failure, or liver disease.

Contact your doctor or health care provider right away if any of these apply to you.

Important:

Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Carry identification to alert health care providers that you are taking Revia . You can get a medication card from your doctor to use for this purpose.

Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Revia.

Contact your health care provider at once if any of the following signs or symptoms of hepatitis occur while taking Revia: stomach pain lasting more than a few days; white bowel movements; dark urine; yellowing of the skin or eyes.

Do not use narcotics while taking Revia, including opioid-containing medicines (e.g., cough and cold products, pain relievers, heroin). Revia may increase your sensitivity to narcotics. Therefore, even very low doses may cause coma or be life-threatening.

Before you have any medical or dental surgery or emergency treatments, tell the doctor or dentist that you are taking Revia.

Lab tests, including liver function, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

Use Revia with extreme caution in children younger than 18 years of age. Safety and effectiveness in this age group have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, discuss with your doctor the benefits and risks of using Revia during pregnancy. It is unknown if Revia is excreted in breast milk. If you are or will be breast-feeding while you are using Revia, check with your doctor or pharmacist to discuss the risks to your baby.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

  • anxiety;
  • appetite loss;
  • chills;
  • constipation;
  • delayed ejaculation;
  • diarrhea;
  • dizziness;
  • drowsiness;
  • feeling down;
  • headache;
  • increased energy;
  • increased thirst;
  • irritability;
  • joint and muscle pain;
  • low energy;
  • nausea;
  • nervousness;
  • sleeplessness;
  • stomach pain/cramps;
  • vomiting.

Seek medical attention right away if any of these severe side effects occur:

  • severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
  • abdominal or stomach pain;
  • cramping;
  • dark urine;
  • depression;
  • suicidal thoughts or behaviors;
  • unusual tiredness or weakness;
  • vomiting;
  • white bowel movements;
  • yellowing of the skin or eyes.

More Information

Revia is to be used only by the patient for whom it is prescribed. Do not share it with other people.

What is the shelf life of the pills?

  • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
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